NKX2-2
Sign in to saveAlso known as NKX2.2, NKX2B, NK2 homeobox 2
Homeobox protein Nkx-2.2 is a protein that in humans is encoded by the NKX2-2 gene.
Gene data
NKX2-2- Name
- NK2 homeobox 2
- Type
- protein-coding
- Position
- 21,511,017–21,514,070 (−)
- Aliases
- NKX2.2, NKX2B
- Ensembl
- ENSG00000125820
- RefSeq RNA
- NM_001424411.1, NM_001424412.1, NM_002509.4, XM_047440152.1, XM_054323457.1
- RefSeq protein
- NP_001411340.1, NP_001411341.1, NP_002500.1, XP_047296108.1, XP_054179432.1
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
NK2 homeobox 2
- Symbol
- NKX2-2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:21,511,017-21,514,070
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Homeobox protein Nkx-2.2 is a protein that in humans is encoded by the NKX2-2 gene.
Homeobox protein Nkx-2.2 contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Excerpted from Wikipedia’s “NKX2-2” article, available under the CC BY-SA 4.0 licence.