Also known as HRNT1, O-GLCNAC, HINCUT-1, O-linked N-acetylglucosamine (GlcNAc) transferase, OGT1, MRX106, XLID106
protein-coding gene in the species Homo sapiens
Gene data
OGT- Name
- O-linked N-acetylglucosamine (GlcNAc) transferase
- Type
- protein-coding
- Chromosome
- X
- Position
- 71,533,068–71,575,892 (+)
- Aliases
- HINCUT-1, HRNT1, MRX106, O-GLCNAC, OGT1, XLID106
- Ensembl
- ENSG00000147162
- RefSeq RNA
- NM_003605.3, NM_025192.1, NM_181672.3, NM_181673.3
- RefSeq protein
- NP_858058.1, NP_858059.1
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
O-linked N-acetylglucosamine (GlcNAc) transferase
- Symbol
- OGT
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:71,533,068-71,575,892
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- OGT full-length.png
Show 8 more facts
- HomoloGene ID
- 9675
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8473
- genomic start
- 71533104
- chromosome
- human X chromosome
- genomic end
- 71575892
- cytogenetic location
- Xq13.1
- expressed in
- trabecular bone
via Wikidata · CC0