tibolone
Sign in to saveTibolone, sold under the brand name Livial among others, is a medication which is used in menopausal hormone therapy and in the treatment of postmenopausal osteoporosis and endometriosis. The medication is available alone and is not formulated or used in combination with other medications. It is taken by mouth.
Key facts
- Drug.legal_AU
- S4
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 470610138
- Drug.image
- Tibolone.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 225
- Drug.image2
- Tibolone molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 235
- Drug.tradename
- Livial, Tibella, Tibofem, others
- Drug.pregnancy_AU
- D
- Drug.routes_of_administration
- By mouth
- Drug.class
- Progestogen; Progestin; Estrogen; Androgen; Anabolic steroid
- Drug.ATC_prefix
- G03
- Drug.ATC_suffix
- CX01
- Drug.legal_CA
- Schedule IV
- Drug.legal_UK
- POM
via Wikipedia infobox
Article
20 sectionsContents
- Medical uses
- Available forms
- Side effects
- Pharmacology
- Pharmacodynamics
- Estrogenic activity
- Progestogenic activity
- Androgenic activity
- Other activities
- Pharmacokinetics
- Chemistry
- Synthesis
- History
- Society and culture
- Generic names
- Brand names
- Availability
- Legal status
- References
- Further reading
Tibolone, sold under the brand name Livial among others, is a medication which is used in menopausal hormone therapy and in the treatment of postmenopausal osteoporosis and endometriosis. The medication is available alone and is not formulated or used in combination with other medications. It is taken by mouth.
Side effects of tibolone include acne and increased hair growth among others. Tibolone is a synthetic steroid with weak estrogenic, progestogenic, and androgenic activity, and hence is an agonist of the estrogen, progesterone, and androgen receptors. It is a prodrug of several metabolites. The estrogenic effects of tibolone may show tissue selectivity in their distribution.