Structure via PubChem · Public domain (PubChem)
pamidronic acid
Sign in to saveAlso known as ARD233, Aredia®, CGP-23339AE, pamidronate, Acide pamidronique, Acidum pamidronicum, Pamidronate
chemical compound
Chemical data
- Formula
- C3H11NO7P2
- Molecular weight
- 235.07 g/mol
- IUPAC name
- (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
- SMILES
- C(CN)C(O)(P(=O)(O)O)P(=O)(O)O
- InChIKey
- WRUUGTRCQOWXEG-UHFFFAOYSA-N
- XLogP
- -6.9
- Polar surface area
- 161 Ų
- H-bond donors
- 6
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1991
- Admin. routes
- parenteral
- Indications
- bone disease, multiple myeloma, osteoporosis, Low back pain
via ChEMBL · EBI
Research
3,481 papers- Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2001
- Atrial fibrillation in patients treated with intravenous zoledronic or pamidronic acid: a pharmacoepidemiological study.European journal of endocrinology · 2021
- Preparation, Optimisation, and In Vitro Evaluation of [(18)F]AlF-NOTA-Pamidronic Acid for Bone Imaging PET.Molecules (Basel, Switzerland) · 2022
- Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2003
- Preparation, Characterization, and Radiolabeling of [(68)Ga]Ga-NODAGA-Pamidronic Acid: A Potential PET Bone Imaging Agent.Molecules (Basel, Switzerland) · 2020
via PubMed
Wikidata facts
- Subclass of
- bisphosphonate
- Mass
- 235.001
- Has use
- medication
Show 5 more facts
- defined daily dose
- 60
- chemical formula
- C₃H₁₁NO₇P₂
- World Health Organisation international non-proprietary name
- pamidronic acid
- medical condition treated
- mammary Paget's disease
- canonical SMILES
- C(CN)C(O)(P(=O)(O)O)P(=O)(O)O
Sources (6)
via Wikidata · CC0