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EntityQ7363297· pop 13· linked from 102 articles

Romosozumab

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Romosozumab, sold under the brand name Evenity ( or with the pin-pen merger, ), is a medication used to treat osteoporosis. It has been found to decrease the risk of fractures of the spine.

Key facts

Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
464383486
Drug.type
mab
Drug.mab_type
mab
Drug.source
zu/o
Drug.target
Sclerostin
Drug.tradename
Evenity
Drug.MedlinePlus
a619026
Drug.DailyMedID
Romosozumab
Drug.pregnancy_AU
B3
Drug.ATC_prefix
M05
Drug.ATC_suffix
BX06
Drug.legal_AU
S4
Drug.legal_CA
Rx-only
Drug.legal_CA_comment
/ Schedule D
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only

via Wikipedia infobox

~3 min read

Encyclopedic overview

4 sections
Contents
  • Medical uses
  • Side effects
  • History
  • References

Romosozumab, sold under the brand name Evenity ( or with the pin-pen merger, ), is a medication used to treat osteoporosis. It has been found to decrease the risk of fractures of the spine.

Common side effects include headache, joint pain, and injection site reactions including pain. It may increase the risk of heart attacks, strokes, and deaths from cardiovascular disease. It is a humanized monoclonal antibody that targets sclerostin. Research shows the drug increases bone formation and decreases bone resorption in postmenopausal women with low bone density. Romosozumab was approved for medical use in Japan, the United States and the European Union in 2019.

Excerpted from Wikipedia’s “Romosozumab” article, available under the CC BY-SA 4.0 licence.