pancreatic polypeptide

Protein · UniProt

Pancreatic polypeptide prohormone

Gene

PPY

Organism

Homo sapiens (Human)

Length

95 aa

Molecular mass

10,445 Da

Evidence

1: Evidence at protein level

Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2

• Pancreatic polypeptide revisited: Potential therapeutic effects in obesity-diabetes.Peptides · 2023
• Pancreatic polypeptide.Clinics in gastroenterology · 1980
• The role of pancreatic polypeptide in pancreatic diseases.Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2017
• Pancreatic polypeptide: more than just another gut hormone?Gastroenterology · 2003
• Pancreatic polypeptide. A review.Archives of surgery (Chicago, Ill. : 1960) · 1981

via PubMed

• PHASE1COMPLETED
  The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin SecretionWashington University School of Medicine · NCT01951729
• PHASE1COMPLETED
  Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic CancerNational Cancer Institute (NCI) · NCT00005842
• PHASE2TERMINATED
  Internal Radiation Therapy in Treating Patients With Liver Metastases From Neuroendocrine TumorsVanderbilt-Ingram Cancer Center · NCT00466856
• PHASE1COMPLETED
  A First-Time-in-Human Study to Assess the Safety and Tolerability of PP 1420 in Healthy SubjectsImperial College London · NCT01052493
• PHASE3COMPLETED
  Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainINSYS Therapeutics Inc · NCT00538850
• NACOMPLETED
  Glucolipotoxicity and Type 2 DiabetesRigshospitalet, Denmark · NCT01375270

via ClinicalTrials.gov