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angiotensins

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angiotensins

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Also known as angiotensin

Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. It is part of the renin–angiotensin system, which regulates blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex to promote sodium retention by the kidneys.

Research

164,911 papers

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Encyclopedic overview

19 sections
Contents
  • Precursor and types
  • Angiotensinogen
  • Angiotensin I
  • Angiotensin II
  • Production
  • Degradation
  • Physiological effects
  • Pharmacological significance
  • Angiotensin III
  • Angiotensin IV
  • Adipic
  • Cardiovascular
  • Neural
  • Adrenal
  • Renal
  • See also
  • References
  • Further reading
  • External links

Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. It is part of the renin–angiotensin system, which regulates blood pressure. Angiotensin also stimulates the release of aldosterone from the adrenal cortex to promote sodium retention by the kidneys.

An oligopeptide, angiotensin is a hormone and a dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. Angiotensin was isolated in the late 1930s (first named "angiotonin" or "hypertensin", later renamed "angiotensin" as a consensus by the 2 groups that independently discovered it) and subsequently characterized and synthesized by groups at the Cleveland Clinic and Ciba laboratories.

Excerpted from Wikipedia’s “angiotensins” article, available under the CC BY-SA 4.0 licence.

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