PEBP1
Sign in to saveAlso known as HCNP, HCNPpp, HEL-210, HEL-S-34, PBP, PEBP, PEBP-1, RKIP
protein-coding gene in the species Homo sapiens
In the Vinony graph
Vinony's link graph records 7 inbound references to PEBP1, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Vinony links it to 5 Wikipedia language editions.
Gene data
PEBP1- Name
- phosphatidylethanolamine binding protein 1
- Type
- protein-coding
- Position
- 118,136,066–118,150,564 (+)
- Aliases
- HCNP, HCNPpp, HEL-210, HEL-S-34, HEL-S-96, PBP, PEBP, PEBP-1, RKIP
- Ensembl
- ENSG00000089220
- RefSeq RNA
- NM_002567.4
- RefSeq protein
- NP_002558.1
This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
phosphatidylethanolamine binding protein 1
- Symbol
- PEBP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:118,136,066-118,150,564
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PEBP1 PDB 1a44.png
Show 7 more facts
- HomoloGene ID
- 37637
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5037
- genomic end
- 118583389
- genomic start
- 118136124
- chromosome
- human chromosome 12
- cytogenetic location
- 12q24.23
Sources (4)
via Wikidata · CC0