AVPR1B
Sign in to saveAlso known as AVPR3, arginine vasopressin receptor 1B, V1bR, VPR3, vasopressin 3 receptor, antidiuretic hormone receptor 1B
protein-coding gene in the species Homo sapiens
Gene data
AVPR1B- Name
- arginine vasopressin receptor 1B
- Type
- protein-coding
- Position
- 206,106,936–206,117,699 (−)
- Aliases
- AVPR3, V1bR, VPR3
- Ensembl
- ENSG00000198049
- RefSeq RNA
- NM_000707.5
- RefSeq protein
- NP_000698.1
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
arginine vasopressin receptor 1B
- Symbol
- AVPR1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:206,106,936-206,117,699
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 22678
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/553
- chromosome
- human chromosome 1
- genomic start
- 206106936
- genomic end
- 206231639
- cytogenetic location
- 1q32.1
- expressed in
- ganglionic eminence
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