Structure via PubChem · Public domain (PubChem)
بيغابتانيب
Sign in to saveAlso known as Pegaptanib Octasodium, NX1838, Pegaptanib sodium, EYE 001, NX 1838
مركب كيميائي ودواء
Chemical data
- Formula
- C20H40N3NaO10P
- Molecular weight
- 536.5 g/mol
- SMILES
- COCCOC(=O)NCCCC[C@@H](C(=O)NCCCCCOP(=O)(C)O)NC(=O)OCCOC.[Na]
- InChIKey
- HZXSQIHZPVCLDJ-LMOVPXPDSA-N
- Polar surface area
- 171 Ų
- H-bond donors
- 4
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2004
- Admin. routes
- parenteral
- Indications
- age-related macular degeneration, retinal vein occlusion, macular degeneration, wet macular degeneration
via ChEMBL · EBI
Research
688 papers- Pegaptanib.2006
- Pegaptanib sodium for the treatment of neovascular age-related macular degeneration: a review.Clinical therapeutics · 2006
- Pegaptanib sodium.Nature reviews. Drug discovery · 2005
- Pegaptanib and ranibizumab for neovascular age-related macular degeneration: a systematic review.The British journal of ophthalmology · 2007
- Pegaptanib: the first antiangiogenic agent approved for neovascular macular degeneration.Expert opinion on pharmacotherapy · 2005
via PubMed
Wikidata facts
- Mass
- 536.2349
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₀H₄₀N₃NaO₁₀P
- canonical SMILES
- COCCOC(=O)NCCCCC(C(=O)NCCCCCOP(=O)(C)O)NC(=O)OCCOC.[Na]
- NCI Thesaurus ID
- C90657
- isomeric SMILES
- COCCOC(=O)NCCCC[C@@H](C(=O)NCCCCCOP(=O)(C)O)NC(=O)OCCOC.[Na]
- has characteristic
- biopharmaceutical
Sources (2)
via Wikidata · CC0