PEX10

Also known as NALD, PBD6A, PBD6B, RNF69, peroxisomal biogenesis factor 10

Peroxisome biogenesis factor 10 is a protein that in humans is encoded by the PEX10 gene. Alternative splicing results in two transcript variants encoding different isoforms.

Gene data

PEX10

Name: peroxisomal biogenesis factor 10
Type: protein-coding
Position: 2,403,784–2,413,797 (−)
Aliases: NALD, PBD6A, PBD6B, RNF69
Ensembl: ENSG00000157911
RefSeq RNA: NM_001374425.1, NM_001374426.1, NM_001374427.1, NM_002617.4, NM_153818.2
RefSeq protein: NP_001361354.1, NP_001361355.1, NP_001361356.1, NP_002608.1, NP_722540.1

This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Pathways

Peroxisome - Homo sapiens (human)Metabolism of proteins Post-translational protein modification Protein ubiquitination E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Protein localization Protein localization Male infertility

via MyGene.info

Gene · Ensembl

peroxisomal biogenesis factor 10

Symbol: PEX10
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:2,403,784-2,413,797
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

exact match: identifiers.org/ncbigene/5192
HomoloGene ID: 5671
found in taxon: Homo sapiens
genomic end: 2345236
genomic start: 2336236
chromosome: human chromosome 1
cytogenetic location: 1p36.32
genetic association: Zellweger syndrome

Sources (5)

via Wikidata · CC0

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Encyclopedic overview

6 sections

Contents

Function
Clinical significance
Interactions
References
Further reading
External links

Peroxisome biogenesis factor 10 is a protein that in humans is encoded by the PEX10 gene. Alternative splicing results in two transcript variants encoding different isoforms.

== Function ==

Excerpted from Wikipedia’s “PEX10” article, available under the CC BY-SA 4.0 licence.