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GeneQ18037763· pop 5· linked from 71 articles

MPC2

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Also known as BRP44, mitochondrial pyruvate carrier 2, SLC54A2

protein-coding gene in the species Homo sapiens

Gene data

MPC2

Name: mitochondrial pyruvate carrier 2
Type: protein-coding
Position: 167,916,675–167,937,515 (−)
Aliases: BRP44, SLC54A2
Ensembl: ENSG00000143158
RefSeq RNA: NM_001143674.4, NM_015415.3, NR_026550.3, XM_006711266.4, XM_054335856.1
RefSeq protein: NP_001137146.1, NP_056230.1, XP_006711329.1, XP_054191831.1

Enables identical protein binding activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

pyruvate import into mitochondria pyruvate import into mitochondria pyruvate import into mitochondria

Molecular function

protein binding identical protein binding pyruvate transmembrane transporter activity pyruvate transmembrane transporter activity

Cellular component

nucleus mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane inner mitochondrial membrane protein complex

Pathways

Diabetic cardiomyopathy - Homo sapiens (human)Aerobic respiration and respiratory electron transport Metabolism Pyruvate metabolism Glycolysis and Gluconeogenesis

via MyGene.info

Gene · Ensembl

mitochondrial pyruvate carrier 2

Symbol: MPC2
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:167,916,675-167,937,515
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

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