
thumb|Serine in an amino acid chain, before and after phosphorylation.
thumb|Serine in an amino acid chain, before and after phosphorylation.
A phosphoprotein is a protein that is posttranslationally modified by the attachment of either a single phosphate group, or a complex molecule such as 5'-phospho-DNA, through a phosphate group. The target amino acid is most often serine, threonine, or tyrosine residues (mostly in eukaryotes), or aspartic acid or histidine residues (mostly in prokaryotes).
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).