picoplatin
Sign in to saveAlso known as (SP-4-3)-Amminedichloro(2-methylpyridine)platinium
Picoplatin is a platinum-based antineoplastic agent in clinical development by Poniard Pharmaceuticals (previously NeoRx) for the treatment of patients with solid tumors.
Wikidata facts
- Subclass of
- chemical compound
- Has part
- platinum
- Mass
- 374.986895
Show 2 more facts
- chemical formula
- C₆H₁₀Cl₂N₂Pt
- canonical SMILES
- CC1=CC=CC=N1.N.Cl[Pt]Cl
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Picoplatin is a platinum-based antineoplastic agent in clinical development by Poniard Pharmaceuticals (previously NeoRx) for the treatment of patients with solid tumors.
In Phase I and Phase II clinical trials, picoplatin demonstrated activity in a variety of solid tumors, including lung, ovarian, colorectal and hormone-refractory prostate cancer. However, in Phase III trials, picoplatin failed to hit its primary endpoint for advanced small cell lung cancer. Hopes are now pinned on its use for metastatic colorectal cancer.
Excerpted from Wikipedia’s “picoplatin” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0