PRAM1
Sign in to saveAlso known as PML-RAR, PRAM-1, PML-RARA regulated adaptor molecule 1
PML-RARA-regulated adapter molecule 1 is a protein that in humans is encoded by the PRAM1 gene.
In the Vinony graph
Within Vinony's link graph, PRAM1 is referenced by 3 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PRAM1- Name
- PML-RARA regulated adaptor molecule 1
- Type
- protein-coding
- Position
- 8,490,056–8,502,656 (−)
- Aliases
- PML-RAR, PRAM-1
- Ensembl
- ENSG00000133246
- RefSeq RNA
- NM_032152.5, XM_005272502.3, XM_011528352.3, XM_011528353.3, XM_054322310.1
- RefSeq protein
- NP_115528.4, XP_005272559.1, XP_011526654.1, XP_011526655.1, XP_054178285.1
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
PML-RARA regulated adaptor molecule 1
- Symbol
- PRAM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:8,490,056-8,502,656
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 12963
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/84106
- chromosome
- human chromosome 19
- genomic start
- 8554940
- genomic end
- 8502640
- cytogenetic location
- 19p13.2
- expressed in
- appendix
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
PML-RARA-regulated adapter molecule 1 is a protein that in humans is encoded by the PRAM1 gene.
== Function ==
Excerpted from Wikipedia’s “PRAM1” article, available under the CC BY-SA 4.0 licence.