Structure via PubChem · Public domain (PubChem)
prazitone
Sign in to savePrazitone (, ; developmental code name AGN-511) is a barbiturate derivative described as an antidepressant which was developed in the 1960s. Unlike most barbiturates, it has little or no sedative effects, instead acting as a non-sedating anxiolytic and antidepressant. The dosage range in humans is around 200–600 mg, although higher doses have been used in trials for the treatment of depression associated with Parkinson's disease.
Chemical data
- Formula
- C16H19N3O3
- Molecular weight
- 301.34 g/mol
- IUPAC name
- 5-phenyl-5-(piperidin-2-ylmethyl)-1,3-diazinane-2,4,6-trione
- SMILES
- C1CCNC(C1)CC2(C(=O)NC(=O)NC2=O)C3=CC=CC=C3
- InChIKey
- UGZAKKMLMJITLL-UHFFFAOYSA-N
- XLogP
- 1.4
- Polar surface area
- 87.3 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 301.143
Show 2 more facts
- chemical formula
- C₁₆H₁₉N₃O₃
- canonical SMILES
- C1CCNC(C1)CC2(C(=O)NC(=O)NC2=O)C3=CC=CC=C3
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Prazitone (, ; developmental code name AGN-511) is a barbiturate derivative described as an antidepressant which was developed in the 1960s. Unlike most barbiturates, it has little or no sedative effects, instead acting as a non-sedating anxiolytic and antidepressant. The dosage range in humans is around 200–600 mg, although higher doses have been used in trials for the treatment of depression associated with Parkinson's disease.
== References ==
Excerpted from Wikipedia’s “prazitone” article, available under the CC BY-SA 4.0 licence.