Structure via PubChem · Public domain (PubChem)
phenoxypropazine
Sign in to savePhenoxypropazine (trade name Drazine) is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine family. It was introduced as an antidepressant in 1961, but was subsequently withdrawn in 1966 due to hepatotoxicity concerns.
Chemical data
- Formula
- C9H14N2O
- Molecular weight
- 166.22 g/mol
- IUPAC name
- 1-phenoxypropan-2-ylhydrazine
- SMILES
- CC(COC1=CC=CC=C1)NN
- InChIKey
- QNEXFJFTGQBXBJ-UHFFFAOYSA-N
- XLogP
- 1.1
- Polar surface area
- 47.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 166.110613
- Has use
- medication
Show 3 more facts
- chemical formula
- C₉H₁₄N₂O
- canonical SMILES
- CC(COC1=CC=CC=C1)NN
- Commons category
- Phenoxypropazine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Phenoxypropazine (trade name Drazine) is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine family. It was introduced as an antidepressant in 1961, but was subsequently withdrawn in 1966 due to hepatotoxicity concerns.
==See also== Hydrazine (antidepressant)
Excerpted from Wikipedia’s “phenoxypropazine” article, available under the CC BY-SA 4.0 licence.