cianopramine
Sign in to saveCianopramine (INN; development code Ro 11-2465; also known as 3-cyanoimipramine) is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor and weak serotonin receptor antagonist. It was investigated for the treatment of depression but was never marketed.
Research
62 papers- A controlled trial of amitriptyline and cianopramine in major depression.Clinical therapeutics · 1985
- Cianopramine and amitriptyline in the treatment of depressed patients--a placebo-controlled study.Psychopharmacology · 1985
- Effect of cianopramine, a tricyclic antidepressant, on platelet serotonin uptake and peripheral adrenergic function.Clinical pharmacology and therapeutics · 1984
- [Computer-assisted static and dynamic pupillometry for the characterization of tricyclic antidepressive agent, cianopramine].Arzneimittel-Forschung · 1988
- Acute and chronic treatment with 5-HT reuptake inhibitors differentially modulate emotional responses in anxiety models in rodents.Psychopharmacology · 1994
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 305.189
Show 3 more facts
- chemical formula
- C₂₀H₂₃N₃
- canonical SMILES
- CN(C)CCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)C#N
- subject has role
- serotonin antagonist
Sources (2)
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Encyclopedic overview
2 sectionsContents
- See also
- References
Cianopramine (INN; development code Ro 11-2465; also known as 3-cyanoimipramine) is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor and weak serotonin receptor antagonist. It was investigated for the treatment of depression but was never marketed.
== See also == Clomipramine Cyanodothiepin Cyamemazine
Excerpted from Wikipedia’s “cianopramine” article, available under the CC BY-SA 4.0 licence.