PRDX2

Name

peroxiredoxin 2

Type

protein-coding

Position

12,796,817–12,801,882 (−)

Aliases

HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA

Ensembl

ENSG00000167815

RefSeq RNA

NM_005809.6, NM_181737.1, NM_181738.1

RefSeq protein

NP_005800.3

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013].

via MyGene.info

Gene · Ensembl

peroxiredoxin 2

Symbol

PRDX2

Biotype

Protein coding

Organism

Homo sapiens

Location

19:12,796,817-12,801,882

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein PRDX2 PDB 1qmv.png

via Wikidata · CC0