purpura
Sign in to saveAlso known as petechial rash, purpuric disorder
Purpura () is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. They measure 3–10 mm, whereas petechiae measure less than 3 mm, and ecchymoses greater than 1 cm.
Key facts
- Medical condition (new).name
- Purpura
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- HSP Vasculitis.jpg
- Medical condition (new).caption
- Petechiae and purpura on the lower limb due to infection-associated vasculitis
- Medical condition (new).field
- Dermatology, hematology
via Wikipedia infobox
Research
41,851 papers- Retiform purpura: A diagnostic approach.Journal of the American Academy of Dermatology · 2020
- [Sports purpura].Presse medicale (Paris, France : 1983) · 2012
- [Purpura fulminans].Canadian Medical Association journal · 1969
- Pigmented purpura and cutaneous vascular occlusion syndromes.Anais brasileiros de dermatologia · 2018
- Thrombotic thrombocytopenic purpura.The Journal of the Arkansas Medical Society · 2015
via PubMed
~3 min read
Encyclopedic overview
5 sectionsContents
- Classification
- Etymology and pronunciation
- See also
- References
- External links
Purpura () is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. They measure 3–10 mm, whereas petechiae measure less than 3 mm, and ecchymoses greater than 1 cm.
Purpura is common with typhus and can be present with meningitis caused by meningococci or septicaemia. In particular, meningococcus (Neisseria meningitidis), a Gram-negative diplococcus organism, releases endotoxin when it lyses. Endotoxin activates the Hageman factor (clotting factor XII), which causes disseminated intravascular coagulation (DIC). The DIC is what appears as a rash on the affected individual.
Excerpted from Wikipedia’s “purpura” article, available under the CC BY-SA 4.0 licence.