cryoglobulinemia
Sign in to saveAlso known as Cryoglobulinaemia, Cryoimmunoglobulinaemia, cryoglobulinemy
Cryoglobulinemia is a rare medical condition characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins composed of immunoglobulins and sometimes complement components. Cryoglobulins specifically form gel-like solids by clumping together and becoming insoluble at temperatures below 37 °C.
Key facts
- Medical condition.name
- Cryoglobulinemia
- Medical condition.synonyms
- Cryoglobulinaemia, cryoglobulinemic disease
- Medical condition.image
- Cryoglobulinemia2.jpg
- Medical condition.caption
- Purpuric skin lesions seen in a person with cryoglobulinemia
- Medical condition.field
- Hematology
via Wikipedia infobox
Research
5,305 papers- Cryoglobulinemia: An update in 2019.Joint bone spine · 2019
- Cryoglobulinemia.Medicina clinica · 2022
- Cryoglobulinemia and double-filtration plasmapheresis: Personal experience and literature review.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2023
- [Cryoglobulinemia].La Revue du praticien · 1993
- Cryoglobulinaemia.Nature reviews. Disease primers · 2018
via PubMed
Wikidata facts
- Instance of
- symptom or sign
- Subclass of
- disease
- Image
- Cryoglobulinemia2.jpg
Show 8 more facts
- health specialty
- cardiology
- NCI Thesaurus ID
- C26736
- ICPC 2 ID
- B99
- exact match
- purl.obolibrary.org/obo/HP_0100778
- Commons category
- Cryoglobulinemia
- drug or therapy used for treatment
- rituximab
- ICD-9-CM
- 273.2
- on focus list of Wikimedia project
- WikiProject Medicine
via Wikidata · CC0
~23 min read
Encyclopedic overview
16 sectionsContents
- Classification
- Signs and symptoms
- Essential cryoglobulinemic disease
- Type I cryoglobulinemic disease
- Types II and III cryoglobulinemic disease
- Mechanism
- Cryoglobulins
- Diagnosis
- Treatment
- Asymptomatic cryoglobulinemia
- Severely symptomatic cryoglobulinemic disease
- Type I cryoglobulinemic disease
- Type II and III cryoglobulinemic disease
- See also
- References
- External links
Cryoglobulinemia is a rare medical condition characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins composed of immunoglobulins and sometimes complement components. Cryoglobulins specifically form gel-like solids by clumping together and becoming insoluble at temperatures below 37 °C.
In the human body, these cryoglobulins precipitate together in small- and medium-sized blood vessels causing occlusions and triggering inflammatory reactions. This leads to a range of symptoms, including joint pain, skin rashes, and kidney problems.
Excerpted from Wikipedia’s “cryoglobulinemia” article, available under the CC BY-SA 4.0 licence.