RAB21

Name

RAB21, member RAS oncogene family

Type

protein-coding

This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015].

via MyGene.info

Gene · Ensembl

RAB21, member RAS oncogene family

Symbol

RAB21

Biotype

Protein coding

Organism

Homo sapiens

Location

12:71,754,835-71,800,286

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein RAB21 PDB 1yzt.png

via Wikidata · CC0