Gene data
RAB21- Name
- RAB21, member RAS oncogene family
- Type
- protein-coding
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015].
via MyGene.info
Gene · Ensembl
RAB21, member RAS oncogene family
- Symbol
- RAB21
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:71,754,835-71,800,286
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein RAB21 PDB 1yzt.png
Show 5 more facts
- HomoloGene ID
- 8991
- exact match
- identifiers.org/ncbigene/23011
- genomic end
- 71800286
- genomic start
- 71754863
- cytogenetic location
- 12q21.1
Sources (4)
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 12
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
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gene
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chromosome
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digital object identifier
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bibcode
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human genome
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Q229883
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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Protein Data Bank
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Q22908627
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Entrez
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Q905695
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Gene Ontology
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