RAB21
Sign in to saveAlso known as RAB21, member RAS oncogene family
Ras-related protein Rab-21 is a protein that in humans is encoded by the RAB21 gene.
Gene data
RAB21- Name
- RAB21, member RAS oncogene family
- Type
- protein-coding
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015].
via MyGene.info
Wikidata facts
- Image
- Protein RAB21 PDB 1yzt.png
Show 5 more facts
- HomoloGene ID
- 8991
- exact match
- identifiers.org/ncbigene/23011
- genomic end
- 71800286
- genomic start
- 71754863
- cytogenetic location
- 12q21.1
Sources (4)
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- References
- Further reading
Ras-related protein Rab-21 is a protein that in humans is encoded by the RAB21 gene.
==References==