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retrotransposon
ProteinQ413988· pop 23· linked from 290 articles

retrotransposon

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Also known as transposons via RNA intermediates, retrotransposons, Class I TE, copy and paste transposable element, copy and paste TE, retroelements

thumb|right|440px|Simplified representation of the life cycle of a retrotransposon

~15 min read

Encyclopedic overview

12 sections
Contents
  • LTR retrotransposons
  • Endogenous retrovirus
  • Non-LTR retrotransposons
  • LINE
  • Human L1
  • SINE
  • Alu elements
  • SVA elements
  • Role in human disease
  • Role in evolution
  • See also
  • References

thumb|right|440px|Simplified representation of the life cycle of a retrotransposon

Retrotransposons (also called Class I transposable elements) are mobile elements which move in the host genome by converting their transcribed RNA into DNA through reverse transcription. Thus, they differ from Class II transposable elements, or DNA transposons, in utilizing an RNA intermediate for the transposition and leaving the transposition donor site unchanged.

Excerpted from Wikipedia’s “retrotransposon” article, available under the CC BY-SA 4.0 licence.

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