RFC5
Sign in to saveAlso known as RFC36, replication factor C subunit 5
Replication factor C subunit 5 is a protein that in humans is encoded by the RFC5 gene.
Gene data
RFC5- Name
- replication factor C subunit 5
- Type
- protein-coding
- Aliases
- RFC36
This gene encodes the smallest subunit of the replication factor C complex, which consists of five distinct subunits (140, 40, 38, 37, and 36 kDa) and is required for DNA replication. This subunit interacts with the C-terminal region of proliferating cell nuclear antigen and is required to open and load proliferating cell nuclear antigen onto DNA during S phase. It is a member of the AAA+ (ATPases associated with various cellular activities) ATPase family and forms a core complex with the 38 and 40 kDa subunits that possesses DNA-dependent ATPase activity. A related pseudogene has been identified on chromosome 9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 6730
- exact match
- identifiers.org/ncbigene/5985
- genomic end
- 118470935
- genomic start
- 118451393
- cytogenetic location
- 12q24.23
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Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Replication factor C subunit 5 is a protein that in humans is encoded by the RFC5 gene.
== Function ==