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GeneQ18031109· pop 5· linked from 812 articles

RFX4

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Also known as NYD-SP10, regulatory factor X4

Transcription factor RFX4 is a protein that in humans is encoded by the RFX4 gene.

Gene data

RFX4
Name
regulatory factor X4
Type
protein-coding
Position
106,582,691–106,762,803 (+)
Aliases
NYD-SP10
Ensembl
ENSG00000111783
RefSeq RNA
NM_001206691.2, NM_002920.3, NM_032491.6, NM_213594.3
RefSeq protein
NP_001193620.1, NP_115880.2, NP_998759.1

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011].

Gene Ontology

Cellular component

chromatinnucleusnucleus

via MyGene.info

Gene · Ensembl

regulatory factor X4

Symbol
RFX4
Biotype
Protein coding
Organism
Homo sapiens
Location
12:106,582,691-106,762,803
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

3 sections
Contents
  • References
  • Further reading
  • External links

Transcription factor RFX4 is a protein that in humans is encoded by the RFX4 gene.

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.

Excerpted from Wikipedia’s “RFX4” article, available under the CC BY-SA 4.0 licence.

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