RHOD
Sign in to saveAlso known as ARHD, RHOHP1, RHOM, Rho, ras homolog family member D
RhoD (Ras homolog gene family, member D) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. It is encoded by the gene RHOD.
Gene data
RHOD- Name
- ras homolog family member D
- Type
- protein-coding
- Position
- 67,056,608–67,072,044 (+)
- Aliases
- ARHD, RHOHP1, RHOM, Rho
- Ensembl
- ENSG00000173156
- RefSeq RNA
- NM_001300886.2, NM_014578.4
- RefSeq protein
- NP_001287815.1, NP_055393.1
Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ras homolog family member D
- Symbol
- RHOD
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:67,056,608-67,072,044
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
RhoD (Ras homolog gene family, member D) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. It is encoded by the gene RHOD.
It binds GTP and is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton.
Excerpted from Wikipedia’s “RHOD” article, available under the CC BY-SA 4.0 licence.