SERPINF2

Name

serpin family F member 2

Type

protein-coding

Position

1,742,069–1,755,271 (+)

Aliases

A2AP, AAP, ALPHA-2-PI, API, PLI, alpha2AP

Ensembl

ENSG00000167711

RefSeq RNA

NM_000934.4, NM_001165920.1, NM_001165921.2, XM_005256701.5, XM_017024765.2

RefSeq protein

NP_000925.2, NP_001159392.1, NP_001159393.1, XP_005256758.2, XP_016880254.1

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

via MyGene.info

Gene · Ensembl

serpin family F member 2

Symbol

SERPINF2

Biotype

Protein coding

Organism

Homo sapiens

Location

17:1,742,069-1,755,271

Strand

Forward (+)

Assembly

GRCh38