ROBO2
Sign in to saveAlso known as SAX3, roundabout guidance receptor 2
Roundabout homolog 2 is a protein that in humans is encoded by the ROBO2 gene.
In the Vinony graph
Vinony's link graph records 8 inbound references to ROBO2, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 3.
Vinony links it to 7 Wikipedia language editions.
Gene data
ROBO2- Name
- roundabout guidance receptor 2
- Type
- protein-coding
- Aliases
- SAX3
The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
via MyGene.info
Gene · Ensembl
roundabout guidance receptor 2
- Symbol
- ROBO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:75,906,667-77,649,964
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ROBO2 PDB 1uem.png
Show 9 more facts
- HomoloGene ID
- 43188
- genomic end
- 77649964
- genetic association
- periodontitis
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6092
- genomic start
- 75955846
- chromosome
- human chromosome 3
- cytogenetic location
- 3p12.3
- expressed in
- gonad
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Roundabout homolog 2 is a protein that in humans is encoded by the ROBO2 gene.
== References ==
Excerpted from Wikipedia’s “ROBO2” article, available under the CC BY-SA 4.0 licence.