SEMA3C
Sign in to saveAlso known as SEMAE, SemE, semaphorin 3C
Semaphorin-3C is a protein that in humans is encoded by the SEMA3C gene.
In the Vinony graph
Vinony's link graph records 5 inbound references to SEMA3C, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Vinony links it to 5 Wikipedia language editions.
Gene data
SEMA3C- Name
- semaphorin 3C
- Type
- protein-coding
- Aliases
- SEMAE, SemE
This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017].
via MyGene.info
Gene · Ensembl
semaphorin 3C
- Symbol
- SEMA3C
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:80,742,538-80,922,393
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 36201
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10512
- chromosome
- human chromosome 7
- genomic start
- 80371854
- genomic end
- 80551675
- cytogenetic location
- 7q21.11
- expressed in
- biceps brachii
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Semaphorin-3C is a protein that in humans is encoded by the SEMA3C gene.
== References ==
Excerpted from Wikipedia’s “SEMA3C” article, available under the CC BY-SA 4.0 licence.