SERINC3

Also known as AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1, serine incorporator 3

Serine incorporator 3 is a protein that in humans is encoded by the SERINC3 gene. It has been demonstrated that SERINC3 acts as a retrovirus restriction factor.

Gene data

SERINC3

Name: serine incorporator 3
Type: protein-coding
Position: 44,496,221–44,522,094 (−)
Aliases: AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1
Ensembl: ENSG00000132824
RefSeq RNA: NM_006811.4, NM_198941.3
RefSeq protein: NP_006802.1, NP_945179.1

Predicted to enable L-serine transmembrane transporter activity. Involved in defense response to virus; detection of virus; and innate immune response. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

L-serine metabolic process plasma membrane phospholipid scrambling antiviral innate immune response

Molecular function

protein binding phospholipid scramblase activity molecular carrier activity

Cellular component

Golgi membrane Golgi apparatus plasma membrane plasma membrane plasma membrane membrane membrane perinuclear region of cytoplasm

Pathways

Metabolism Metabolism of amino acids and derivatives Serine metabolism

via MyGene.info

Wikidata facts

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HomoloGene ID: 38230
exact match: identifiers.org/ncbigene/10955
genomic end: 44522085
genomic start: 43124862
cytogenetic location: 20q13.12

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Serine incorporator 3 is a protein that in humans is encoded by the SERINC3 gene. It has been demonstrated that SERINC3 acts as a retrovirus restriction factor.

== References ==