SNX1

Also known as HsT17379, VPS5, sorting nexin 1

Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene. The protein encoded by this gene is a sorting nexin. SNX1 is a component of the retromer complex.

Gene data

SNX1

Name: sorting nexin 1
Type: protein-coding
Aliases: HsT17379, VPS5

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image: PDB 2i4k EBI.png

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HomoloGene ID: 99716
exact match: identifiers.org/ncbigene/6642
genomic end: 64438289
genomic start: 64386322
cytogenetic location: 15q22.31

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Function
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Sorting nexin-1 is a protein that in humans is encoded by the SNX1 gene. The protein encoded by this gene is a sorting nexin. SNX1 is a component of the retromer complex.

== Function ==