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GeneQ18033246· pop 5· linked from 25 articles

Also known as Grd19, MCOPS8, SDP3, sorting nexin 3

Sorting nexin-3 is a protein that in humans is encoded by the SNX3 gene.

Gene data

SNX3
Name
sorting nexin 3
Type
protein-coding
Position
108,210,873–108,261,255 (−)
Aliases
Grd19, MCOPS8, SDP3
RefSeq RNA
NM_001300928.2, NM_001300929.2, NM_003795.6, NM_152827.4, NM_152828.2
RefSeq protein
NP_001287857.1, NP_001287858.1, NP_003786.1, NP_690040.1

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014].

via MyGene.info

Gene · Ensembl

sorting nexin 3

Symbol
SNX3
Biotype
Protein coding
Organism
Homo sapiens
Location
6:108,210,873-108,261,255
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
36144
genomic end
108582464
found in taxon
Homo sapiens
genomic start
108532426
cytogenetic location
6q21
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Sorting nexin-3 is a protein that in humans is encoded by the SNX3 gene.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.

Excerpted from Wikipedia’s “SNX3” article, available under the CC BY-SA 4.0 licence.

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