Structure via PubChem · Public domain (PubChem)
sodium stibogluconate
Sign in to saveAlso known as Stibinol, Stibanate, Antimony sodium gluconate, Stibatin, Trisodium 1-{[3-carboxylato-5-(1,2-dihydroxyethyl)-1-hydroxy-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]hept-1-yl]oxy}-5-(1,2-dihydroxyethyl)-1-oxido-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]heptane-3-carboxylate nonahydrate, Antimony (v) derivative OF sodium gluconate, Myostibin, Stibogluconate de sodium
pharmaceutical drug
Chemical data
- Formula
- C12H35Na3O26Sb2
- Molecular weight
- 907.88 g/mol
- IUPAC name
- trisodium;(4R,5S,6R)-2-[[(4R,5S,6R)-4-carboxylato-5-hydroxy-6-[(1R)-1-hydroxy-2-oxidoethyl]-2-oxo-1,3,2lambda5-dioxastibinan-2-yl]oxy]-6-[(1R)-1,2-dihydroxyethyl]-5-hydroxy-2-oxo-1,3,2lambda5-dioxastibinane-4-carboxylate;nonahydrate
- SMILES
- C([C@H]([C@@H]1[C@@H]([C@@H](O[Sb](=O)(O1)O[Sb]2(=O)O[C@@H]([C@@H]([C@@H](O2)C(=O)[O-])O)[C@@H](C[O-])O)C(=O)[O-])O)O)O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+]
- InChIKey
- YULOXSGQUSZUMS-UZVLBLASSA-L
- Polar surface area
- 294 Ų
- H-bond donors
- 14
- H-bond acceptors
- 26
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,350 papers- Sodium stibogluconate.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2006
- Sodium stibogluconate and CD47-SIRPα blockade overcome resistance of anti-CD20-opsonized B cells to neutrophil killing.Blood advances · 2022
- Recommendations for treating leishmaniasis with sodium stibogluconate (Pentostam) and review of pertinent clinical studies.The American journal of tropical medicine and hygiene · 1992
- Effect of sodium stibogluconate in recruiting and awakening immune cells in the pleural fluid of pancreatic cancer: preparation for immunotherapy.Frontiers in immunology · 2023
- Repurposing sodium stibogluconate as an uracil DNA glycosylase inhibitor against prostate cancer using a time-resolved oligonucleotide-based drug screening platform.Bioorganic chemistry · 2024
via PubMed
Wikidata facts
- Subclass of
- mixture
- Mass
- 907.8802
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₂H₃₅Na₃O₂₆Sb₂
- World Health Organisation international non-proprietary name
- sodium stibogluconate
- defined daily dose
- 0.85
- subject has role
- bactericide
- isomeric SMILES
- O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].OC[C@@H](O)[C@H]1O[Sb](=O)(O[Sb]2(=O)O[C@H]([C@H](O)C[O-])[C@H](O)[C@@H](O2)C(=O)[O-])O[C@H]([C@H]1O)C(=O)[O-]
via Wikidata · CC0