SPATA5

Also known as AFG2, SPAF, EHLMRS, spermatogenesis associated 5, NEDHSB

Spermatogenesis-associated protein 5 is a protein that in humans is encoded by the SPATA5 gene.

In the Vinony graph

Within Vinony's link graph, SPATA5 is referenced by 3 other articles, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 4.

Its subject is documented across 6 Wikipedia language editions.

Gene data

AFG2A

Name: AAA ATPase AFG2A
Type: protein-coding
Position: 122,923,070–123,319,433 (+)
Aliases: AFG2, EHLMRS, NEDHSB, SPAF, SPATA5
Ensembl: ENSG00000145375
RefSeq RNA: NM_001317799.2, NM_001345856.2, NM_001437913.1, NM_001438322.1, NM_145207.3
RefSeq protein: NP_001304728.1, NP_001332785.1, NP_001424842.1, NP_001425251.1, NP_660208.2

This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016].