ARID5B
Sign in to saveAlso known as DESRT, MRF-2, MRF2, AT-rich interaction domain 5B
AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene.
Gene data
ARID5B- Name
- AT-rich interaction domain 5B
- Type
- protein-coding
- Position
- 61,901,684–62,096,944 (+)
- Aliases
- DESRT, MRF-2, MRF2
- Ensembl
- ENSG00000150347
- RefSeq RNA
- NM_001244638.2, NM_032199.3
- RefSeq protein
- NP_001231567.1, NP_115575.1
This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein ARID5B PDB 1ig6.png
Show 5 more facts
- HomoloGene ID
- 45872
- exact match
- identifiers.org/ncbigene/84159
- genomic end
- 63856703
- genomic start
- 61901684
- cytogenetic location
- 10q21.2
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Article
5 sectionsContents
- Genomics
- Clinical importance
- References
- External links
- Further reading
AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene.
Alternative names for this gene include Modulator recognition factor 23.