SPINT1
Sign in to saveAlso known as HAI, HAI1, MANSC2, serine peptidase inhibitor, Kunitz type 1
Kunitz-type protease inhibitor 1 is an enzyme that in humans is encoded by the SPINT1 gene.
Gene data
SPINT1- Name
- serine peptidase inhibitor, Kunitz type 1
- Type
- protein-coding
- Position
- 40,843,513–40,858,383 (+)
- Aliases
- HAI, HAI1, MANSC2
- Ensembl
- ENSG00000166145
- RefSeq RNA
- NM_001032367.2, NM_001386873.1, NM_001386874.1, NM_001386875.1, NM_003710.4
- RefSeq protein
- NP_001027539.1, NP_001373802.1, NP_001373803.1, NP_001373804.1, NP_003701.1
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein SPINT1 PDB 1yc0.png
Show 5 more facts
- HomoloGene ID
- 9653
- exact match
- identifiers.org/ncbigene/6692
- genomic end
- 41150405
- genomic start
- 41136216
- cytogenetic location
- 15q15.1
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- Further reading
Kunitz-type protease inhibitor 1 is an enzyme that in humans is encoded by the SPINT1 gene.
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.