TAF8
Sign in to saveAlso known as 43, II, TAF, TAFII-43, TAFII43, TBN, TATA-box binding protein associated factor 8, TAF(II)43
Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene.
Gene data
TAF8- Name
- TATA-box binding protein associated factor 8
- Type
- protein-coding
- Aliases
- II, NEDMLHB, TAF, TAF(II)43, TAFII-43, TAFII43, TBN
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 11094
- exact match
- identifiers.org/ncbigene/129685
- genomic end
- 42055199
- genomic start
- 42018251
- cytogenetic location
- 6p21.1
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Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene.
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.