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taleranol

Structure via PubChem · Public domain (PubChem)

EntityQ27116399· pop 5· linked from 578 articles

Also known as teranol, β-zearalanol, P-1560

Taleranol (INN, USAN) (developmental code name P-1560), or teranol, also known as β-zearalanol, is a synthetic, nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp which was never marketed. It is the β epimer of zeranol (α-zearalanol) and is a major metabolite of zeranol but with less biological activity.

Chemical data

Formula
C18H26O5
Molecular weight
322.4 g/mol
IUPAC name
(4S,8S)-8,16,18-trihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-2-one
SMILES
C[C@H]1CCC[C@H](CCCCCC2=C(C(=CC(=C2)O)O)C(=O)O1)O
InChIKey
DWTTZBARDOXEAM-JSGCOSHPSA-N
XLogP
4.3
Polar surface area
87 Ų
H-bond donors
3
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of
macrolides
Mass
322.178
Show 5 more facts
found in taxon
pomegranate
canonical SMILES
CC1CCCC(CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
chemical formula
C₁₈H₂₆O₅
isomeric SMILES
C[C@H]1CCC[C@H](CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
stereoisomer of
zeranol
Sources (2)

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Taleranol (INN, USAN) (developmental code name P-1560), or teranol, also known as β-zearalanol, is a synthetic, nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp which was never marketed. It is the β epimer of zeranol (α-zearalanol) and is a major metabolite of zeranol but with less biological activity.

==See also== α-Zearalenol β-Zearalenol Zearalanone Zearalenone

Excerpted from Wikipedia’s “taleranol” article, available under the CC BY-SA 4.0 licence.

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