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fenarimol
Sign in to saveFenarimol, sold under the tradenames Bloc, Rimidin and Rubigan, is a fungicide which acts against rusts, blackspot and mildew fungi. It is used on ornamental plants, trees, lawns, tomatoes, peppers, eggplants, cucumbers and melons. It is mainly used to control powdery mildew. It works by inhibiting the fungus's biosynthesis of important steroid molecules (via blockade of the CYP51 enzyme).
Chemical data
- Formula
- C17H12Cl2N2O
- Molecular weight
- 331.2 g/mol
- IUPAC name
- (2-chlorophenyl)-(4-chlorophenyl)-pyrimidin-5-ylmethanol
- SMILES
- C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)(C3=CN=CN=C3)O)Cl
- InChIKey
- NHOWDZOIZKMVAI-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 46 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
193 papers- Targeted review of maximum residue levels (MRLs) for fenarimol.EFSA journal. European Food Safety Authority · 2023
- Mode of action of fenarimol against Leishmania spp.The Journal of parasitology · 2008
- Predicting the in vivo developmental toxicity of fenarimol from in vitro toxicity data using PBTK modelling-facilitated reverse dosimetry approach.Toxicology and applied pharmacology · 2024
- Fenarimol, a Pyrimidine-Type Fungicide, Inhibits Brassinosteroid Biosynthesis.International journal of molecular sciences · 2015
- Neurodevelopmental effects of perinatal fenarimol exposure on rats.Reproductive toxicology (Elmsford, N.Y.) · 2007
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 330.033
Show 2 more facts
- chemical formula
- C₁₇H₁₂Cl₂N₂O
- canonical SMILES
- C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)(C3=CN=CN=C3)O)Cl
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- History
- Synthesis
- References
- External links
Fenarimol, sold under the tradenames Bloc, Rimidin and Rubigan, is a fungicide which acts against rusts, blackspot and mildew fungi. It is used on ornamental plants, trees, lawns, tomatoes, peppers, eggplants, cucumbers and melons. It is mainly used to control powdery mildew. It works by inhibiting the fungus's biosynthesis of important steroid molecules (via blockade of the CYP51 enzyme).
==History==
Excerpted from Wikipedia’s “fenarimol” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0