Structure via PubChem · Public domain (PubChem)
thiodiglycol
Sign in to saveAlso known as 2-[(2-hydroxyethyl)sulfanyl]ethan-1-ol, beta,beta'-dihydroxyethyl sulfide, beta-thiodiglycol, beta,beta'-dihydroxydiethyl sulfide, beta-hydroxyethyl sulfid, beta-bis(hydroxyethyl) sulfide, bis(beta-hydroxyethyl) sulfide, Dihydroxyethyl sulfide
Thiodiglycol, or bis(2-hydroxyethyl)sulfide (also known as 2,2-thiodiethanol or TDE), is the organosulfur compound with the formula S(CH2CH2OH)2. It is miscible with water and polar organic solvents. It is a colorless liquid. It is structurally similar to diethylene glycol.
Chemical data
- Formula
- C4H10O2S
- Molecular weight
- 122.19 g/mol
- IUPAC name
- 2-(2-hydroxyethylsulfanyl)ethanol
- SMILES
- C(CSCCO)O
- InChIKey
- YODZTKMDCQEPHD-UHFFFAOYSA-N
- XLogP
- -0.6
- Polar surface area
- 65.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
265 papers- Toxicity assessment of thiodiglycol.International journal of toxicology · 2005
- Non-contact detection of thiodiglycol vapors and associated degradation products using atmospheric flow tube mass spectrometry.The Analyst · 2021
- Oral toxicity evaluation of thiodiglycol in Sprague-Dawley rats.International journal of toxicology · 2014
- Thiodiglycol, the hydrolysis product of sulfur mustard: analysis of in vitro biotransformation by mammalian alcohol dehydrogenases using nuclear magnetic resonance.Toxicology and applied pharmacology · 2006
- [Thiodiglycol metabolism in Alcaligenes xylosoxydans subsp. denitrificans].Mikrobiologiia · 2002
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Mass
- 122.04
Show 6 more facts
- chemical formula
- C₄H₁₀O₂S
- canonical SMILES
- C(CSCCO)O
- World Health Organisation international non-proprietary name
- thiodiglycol
- subject has role
- enzyme inhibitor
- melting point
- -16
- Commons category
- Thiodiglycol
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Thiodiglycol, or bis(2-hydroxyethyl)sulfide (also known as 2,2-thiodiethanol or TDE), is the organosulfur compound with the formula S(CH2CH2OH)2. It is miscible with water and polar organic solvents. It is a colorless liquid. It is structurally similar to diethylene glycol.
Thiodiglycol is manufactured by reaction of 2-chloroethanol with sodium sulfide.
Excerpted from Wikipedia’s “thiodiglycol” article, available under the CC BY-SA 4.0 licence.