enzyme inhibitor
Sign in to saveAlso known as enzyme inhibitors
molecule that binds to an enzyme and decreases its activity
In the Vinony graph
Within Vinony's link graph, enzyme inhibitor is referenced by 8,245 other articles, and connects out to allosteric regulation, covalent bond and legume.
It is catalogued under topics including Biochemical reactions, Enzyme inhibitors and Medicinal chemistry.
Its subject is documented across 34 Wikipedia language editions.
Research
1,993,115 papers- Enzyme inhibitor discovery by activity-based protein profiling.Annual review of biochemistry · 2014
- Enzyme-inhibitor interactions at the plant-pathogen interface.Current opinion in plant biology · 2008
- Label-free flow cytometry-based enzyme inhibitor identification.Analytica chimica acta · 2021
- Class A beta-lactamases--enzyme-inhibitor interactions and resistance.Pharmacology & therapeutics · 1999
- Affimer-Enzyme-Inhibitor Switch Sensor for Rapid Wash-free Assays of Multimeric Proteins.ACS sensors · 2019
via PubMed
Wikidata facts
- Subclass of
- reaction inhibitor
Show 3 more facts
- topic's main category
- Category:Enzyme inhibitors
- Commons category
- Enzyme inhibitors
- physically interacts with
- enzyme
Sources (3)
via Wikidata · CC0
~40 min read
Encyclopedic overview
Top: enzyme (E) accelerates conversion of substrates (S) to products (P). Bottom: by binding to the enzyme, inhibitor (I) blocks binding of substrate. Binding site shown in blue checkerboard, substrate as black rectangle, and inhibitor as green rounded rectangle.
An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity. Enzymes are proteins that speed up chemical reactions necessary for life, in which substrate molecules are converted into products. An enzyme facilitates a specific chemical reaction by binding the substrate to its active site, a specialized area on the enzyme that accelerates the most difficult step of the reaction.
Excerpted from Wikipedia’s “enzyme inhibitor” article, available under the CC BY-SA 4.0 licence.