thrombus
Sign in to saveA thrombus ( thrombi) is a solid or semisolid aggregate from constituents of the blood (platelets, fibrin, red blood cells, white blood cells) within the circulatory system during life. A blood clot is the final product of the blood coagulation step in hemostasis in or out of the circulatory system. There are two components to a thrombus: aggregated platelets and red blood cells that form a plug, and a mesh of cross-linked fibrin protein. The substance making up a thrombus is sometimes called cruor. A thrombus is a healthy response to injury intended to stop and prevent further bleeding, but c
Key facts
- Medical condition (new).name
- Thrombus
- Medical condition (new).synonyms
- Blood clot
- Medical condition (new).image
- Blood clot svg hariadhi.svg
- Medical condition (new).caption
- Diagram of a thrombus (blood clot) that has blocked a vein valve
- Medical condition (new).field
- Vascular surgery, hematology, interventional radiology
- Medical condition (new).symptoms
- abrupt change in mental status, chest pain, cramp-like feeling, fatigue, passing out (syncope), and swelling in the arm and/or leg
- Medical condition (new).complications
- bleeding risks from taking anticoagulants, breathing problems, heart attacks, stroke
- Medical condition (new).duration
- c. 3–6 months
- Medical condition (new).types
- Superficial thrombophlebitis and thrombophlebitis migrans
- Medical condition (new).causes
- injury to the artery, sepsis or viral infection, immobility
- Medical condition (new).risks
- hospitalization, immobility, obesity, pregnancy, physical trauma
- Medical condition (new).diagnosis
- magnetic resonance angiography, ultrasound, and venography
- Medical condition (new).prevention
- smoking cessation, regular exercise, improved blood flow, management of comorbidities
- Medical condition (new).treatment
- Anticoagulants: edoxaban, tinzaparin, unfractionated heparin
- Medical condition (new).medication
- apixaban, edoxaban, and rivaroxaban
- Medical condition (new).deaths
- 100,000–300,000 each year
via Wikipedia infobox
Article
12 sectionsContents
- Classification
- Microclots
- Mural thrombi
- Cause
- Pathophysiology
- Formation
- Prevention
- Treatment
- Prognosis
- See also
- References
- External links
A thrombus ( thrombi) is a solid or semisolid aggregate from constituents of the blood (platelets, fibrin, red blood cells, white blood cells) within the circulatory system during life. A blood clot is the final product of the blood coagulation step in hemostasis in or out of the circulatory system. There are two components to a thrombus: aggregated platelets and red blood cells that form a plug, and a mesh of cross-linked fibrin protein. The substance making up a thrombus is sometimes called cruor. A thrombus is a healthy response to injury intended to stop and prevent further bleeding, but can be harmful in thrombosis, when a clot obstructs blood flow through a healthy blood vessel in the circulatory system.
In the microcirculation consisting of the very small and smallest blood vessels the capillaries, tiny thrombi known as microclots can obstruct the flow of blood in the capillaries. This can cause a number of problems particularly affecting the alveoli in the lungs of the respiratory system resulting from reduced oxygen supply. Microclots have been found to be a characteristic feature in severe cases of COVID-19 and in long COVID.