Structure via PubChem · Public domain (PubChem)
thyronamine
Sign in to saveThyronamine is a type of decarboxylated and deiodinated metabolite of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3). The word thyronamine can refer to either the family of molecules, or the specific molecule from which they are derived.
Chemical data
- Formula
- C14H15NO2
- Molecular weight
- 229.27 g/mol
- IUPAC name
- 4-[4-(2-aminoethyl)phenoxy]phenol
- SMILES
- C1=CC(=CC=C1CCN)OC2=CC=C(C=C2)O
- InChIKey
- OVUVNKDANCKDCK-UHFFFAOYSA-N
- XLogP
- 2.4
- Polar surface area
- 55.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 229.110279
Show 3 more facts
- chemical formula
- C₁₄H₁₅NO₂
- canonical SMILES
- C1=CC(=CC=C1CCN)OC2=CC=C(C=C2)O
- Commons category
- Thyronamine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Types
- See also
- References
Thyronamine is a type of decarboxylated and deiodinated metabolite of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3). The word thyronamine can refer to either the family of molecules, or the specific molecule from which they are derived.
==Types== The group includes: Thyronamine (T0AM) 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), an intracellular G protein-coupled receptor 3,5-Diiodothyronamine (T2AM) 3,5,3'-Triiodothyronamine (T3AM)
Excerpted from Wikipedia’s “thyronamine” article, available under the CC BY-SA 4.0 licence.