Structure via PubChem · Public domain (PubChem)
Tipranavir
Sign in to saveAlso known as U-140690, TPV, 3'-((1R)-1-((6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-phenethyl-6-propyl-2H-pyran-3-yl)propyl)-5-(trifluoromethyl)-2-pyridinesulfonanilide
farmaco
Chemical data
- Formula
- C31H33F3N2O5S
- Molecular weight
- 602.7 g/mol
- IUPAC name
- N-[3-[(1R)-1-[(2R)-4-hydroxy-6-oxo-2-(2-phenylethyl)-2-propyl-3H-pyran-5-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide
- SMILES
- CCC[C@]1(CC(=C(C(=O)O1)[C@H](CC)C2=CC(=CC=C2)NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)O)CCC4=CC=CC=C4
- InChIKey
- SUJUHGSWHZTSEU-FYBSXPHGSA-N
- XLogP
- 7
- Polar surface area
- 114 Ų
- H-bond donors
- 2
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2005
- Admin. routes
- oral
- Indications
- HIV infection, viral disease, hemorrhage
via ChEMBL · EBI
Research
512 papers- Tipranavir.2012
- Tipranavir.2006
- Tipranavir.Drugs · 2003
- Tipranavir.Drugs of today (Barcelona, Spain : 1998) · 2005
- Tipranavir: PNU 140690, tipranivir.Drugs in R&D · 2006
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 602.206
- Has use
- medication
Show 10 more facts
- subject has role
- bactericide
- chemical formula
- C₃₁H₃₃F₃N₂O₅S
- significant drug interaction
- atorvastatin
- canonical SMILES
- CCCC1(CC(=C(C(=O)O1)C(CC)C2=CC(=CC=C2)NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)O)CCC4=CC=CC=C4
- isomeric SMILES
- CCC[C@]1(CC(=C(C(=O)O1)[C@H](CC)C2=CC(=CC=C2)NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)O)CCC4=CC=CC=C4
- World Health Organisation international non-proprietary name
- tipranavir
- defined daily dose
- 1
- medical condition treated
- HIV infection
- Commons category
- Tipranavir
- legal status (medicine)
- boxed warning
Sources (7)
via Wikidata · CC0
Article · Italiano
Il tipranavir è un farmaco antiretrovirale appartenente alla classe degli inibitori delle proteasi di HIV.
Abstract from DBpedia / Wikipedia · CC BY-SA