toltrazuril
Sign in to saveToltrazuril is an antiparasitic medication used primarily to treat coccidiosis in animals. Coccidiosis is a parasitic disease caused by coccidia, which are microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida.
Research
324 papers- Toltrazuril inhibits Toxoplasma gondii by potentially targeting pyrimidine metabolism.Pesticide biochemistry and physiology · 2025
- Toltrazuril + fenbendazole for cattle: Pharmacokinetics and efficacy against Eimeria spp. and gastrointestinal nematodes.Veterinary parasitology, regional studies and reports · 2024
- Metaphylactic strategies using toltrazuril against coccidiosis in goat kids.Veterinary parasitology · 2024
- Migration and toxicity of toltrazuril and its main metabolites in the environment.Chemosphere · 2022
- Toltrazuril and diclazuril: comparative evaluation of anti-coccidial drugs using a murine model.The Journal of veterinary medical science · 2022
via PubMed
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Encyclopedic overview
3 sectionsContents
- Mechanism of action
- Use in veterinary medicine
- References
Toltrazuril is an antiparasitic medication used primarily to treat coccidiosis in animals. Coccidiosis is a parasitic disease caused by coccidia, which are microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida.
== Mechanism of action == Toltrazuril works by interfering with the protozoa's ability to reproduce. It disrupts the division of the protozoal nucleus and damages the cell membrane of the parasites. This action results in the destruction of the coccidia at all stages of their life cycle.
Excerpted from Wikipedia’s “toltrazuril” article, available under the CC BY-SA 4.0 licence.