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EntityQ1992452· pop 15· linked from 80 articles

triptorelin

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Also known as CL 118532, CL-118532, Decapeptyl®, (6-D-Tryptophan)luteinizing hormone-releasing hormone, (D-Trp6)-GnRH, Luteinizing hormone-releasing factor (pig), 6-D-tryptophan, pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2, triptoreline

Triptorelin, sold under the brand name Decapeptyl among others, is a medication that acts as an agonist analog of gonadotropin-releasing hormone, repressing expression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It was patented in 1975 and approved for medical use in 1986. Triptorelin is a therapeutic alternative on the World Health Organization's List of Essential Medicines.

Research

2,460 papers

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Encyclopedic overview

13 sections
Contents
  • Medical uses
  • Drug action
  • Side-effects
  • Society and culture
  • Brand names
  • History
  • Research
  • Dosage in IVF treatment
  • In prostate cancer
  • Pharmacokinetics
  • Gonapeptyl Depot 3.75 mg
  • References
  • Further reading

Triptorelin, sold under the brand name Decapeptyl among others, is a medication that acts as an agonist analog of gonadotropin-releasing hormone, repressing expression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It was patented in 1975 and approved for medical use in 1986. Triptorelin is a therapeutic alternative on the World Health Organization's List of Essential Medicines.

It is a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) and a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts.

Excerpted from Wikipedia’s “triptorelin” article, available under the CC BY-SA 4.0 licence.

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