Structure via PubChem · Public domain (PubChem)
deslorelin
Sign in to saveDeslorelin, sold under the brand name Suprelorin among others, is an injectable gonadotropin releasing hormone superagonist (GnRH agonist) which is used in veterinary medicine for various indications.
Chemical data
- Formula
- C64H83N17O12
- Molecular weight
- 1282.4 g/mol
- IUPAC name
- N-[1-[[1-[[1-[[1-[[1-[[1-[[5-(diaminomethylideneamino)-1-[2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
- SMILES
- CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8
- InChIKey
- GJKXGJCSJWBJEZ-UHFFFAOYSA-N
- XLogP
- 1.1
- Polar surface area
- 447 Ų
- H-bond donors
- 16
- H-bond acceptors
- 14
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Protein
- Indications
- Hereditary breast and ovarian cancer syndrome, precocious puberty
via ChEMBL · EBI
Research
418 papersvia PubMed
Wikidata facts
- Mass
- 1281.640711096
Show 5 more facts
- chemical formula
- C₆₄H₈₃N₁₇O₁₂
- isomeric SMILES
- CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2c[nH]c3c2cccc3)NC(=O)[C@H](Cc4ccc(cc4)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc5c[nH]c6c5cccc6)NC(=O)[C@H](Cc7c[nH]cn7)NC(=O)[C@@H]8CCC(=O)N8
- NCI Thesaurus ID
- C38709
- subject has role
- enzyme inhibitor
- canonical SMILES
- CCNC(=O)C1CCCN1C(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1c[nH]cn1)NC(=O)C1CCC(=O)N1
Sources (1)
via Wikidata · CC0
~3 min read
Encyclopedic overview
8 sectionsContents
- Uses
- Veterinary
- Pharmacology
- Pharmacokinetics
- Chemistry
- History
- Research
- References
Deslorelin, sold under the brand name Suprelorin among others, is an injectable gonadotropin releasing hormone superagonist (GnRH agonist) which is used in veterinary medicine for various indications.
==Uses==
Excerpted from Wikipedia’s “deslorelin” article, available under the CC BY-SA 4.0 licence.