PRKAA1

Name

protein kinase AMP-activated catalytic subunit alpha 1

Type

protein-coding

Position

40,759,389–40,798,374 (−)

Aliases

AMPK, AMPK alpha 1, AMPKa1

Ensembl

ENSG00000132356

RefSeq RNA

NM_001355028.2, NM_001355029.2, NM_001355034.2, NM_001355035.2, NM_001355036.2

RefSeq protein

NP_001341957.1, NP_001341958.1, NP_001341963.1, NP_001341964.1, NP_001341965.1

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

protein kinase AMP-activated catalytic subunit alpha 1

Symbol

PRKAA1

Biotype

Protein coding

Organism

Homo sapiens

Location

5:40,759,389-40,798,374

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein PRKAA1 PDB 2h6d.png

via Wikidata · CC0